AnimalGWASAtlas: Annotation and prioritization of GWAS loci and quantitative trait loci for animal complex traits.

ABSTRACT: Genome-wide association study (GWAS) and quantitative trait locus (QTL) mapping methods provide valuable insights and opportunities for identifying functional gene underlying phenotype formation. However, the majority of GWAS risk loci and QTLs located in noncoding regions poses significant challenges in pinpointing the protein-coding genes associated with specific traits. Moreover, growing evidence suggests not all GWAS risk loci and QTLs are functional, emphasizing the critical need for prioritizing causal sites-a task of paramount importance for biologists. The accumulation of publicly available multiomics data provides an unprecedented opportunity to annotate and prioritize GWAS risk loci and QTLs. Therefore, we developed a comprehensive multiomics database encompassing four major agri

SUBMITTER: Gou Y 

PROVIDER: S-EPMC11904539 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature