Development of a graphene oxide multilayer quantum dot-based immunochromatographic strip for the ultrasensitive detection of H7 subtype avian influenza viruses.

ABSTRACT: Since March 2013, the H7N9 subtype of avian influenza virus (AIV) has become an important zoonotic infectious disease, garnering significant global attention because of its potential to affect human health. Establishing a rapid, effective, and sensitive method to detect H7 subtype AIVs is crucial for disease control. In this study, we developed a graphene oxide multilayer quantum dot-based immunochromatographic strip for the ultrasensitive detection of H7 subtype AIVs. The method demonstrated excellent sensitivity, with a limit of detection of 0.063 hemagglutinin units and 0.016 ng/ml for the hemagglutinin protein. The method exhibited remarkable specificity, with no reaction with other subtypes of influenza A virus andno cross-reactivity with other types of avian virus. Additionally, this

SUBMITTER: Fu J 

PROVIDER: S-EPMC11904543 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature