Intravascular Sympathetic Stimulation to Facilitate Catheter Ablation of Premature Ventricular Complexes.

ABSTRACT:

Importance

Infrequent intraprocedural premature ventricular complexes (PVCs) limit the efficacy of catheter ablation. Intravascular stimulation of sympathetic nerves via vertebral veins (VVs) has been used to activate cardiac sympathetic tone and may promote PVCs.

Objective

To characterize the ability of direct electrical sympathetic stimulation via VVs to induce PVCs at the time of catheter ablation.

Design, setting, and participants

This prospective case series involved adult patients undergoing catheter ablation of PVCs, with rare or absent PVCs despite standard provocation, at the Hospital of the University of Pennsylvania between 2022 and 2024. Stimulation was performed via the left VV (20 Hz, up to 25 mA).

Main outcomes and measures

The primary outcome wa

SUBMITTER: Markman TM 

PROVIDER: S-EPMC11904726 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature