Clinical Characteristics of Cognitive Subgroups of Obsessive Compulsive Disorder.

ABSTRACT:

Introduction

Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder. The results of symptom-based classification studies are inconsistent in resolving this heterogeneity. The aim of this study was to investigate clinical differences between clusters created according to neurocognitive performance.

Methods

This study combined data sets from three previously published studies. A total of 135 outpatients diagnosed with OCD, and 106 healthy controls (HCs) were evaluated using the 17-Item Hamilton Depression Rating Scale (HDRS-17) and a comprehensive neuropsychological battery. Patients were also administered the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).

Results

Two neurocognitive subgroups were identified by k-means cluster analysis: globally imp

SUBMITTER: Mısır E 

PROVIDER: S-EPMC11904946 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature