Association between Triglyceride-Glucose Index and Prognosis in Critically Ill Patients with Acute Coronary Syndrome: Evidence from the MIMIC Database.

ABSTRACT: Background: This study aimed to investigate the association between triglyceride-glucose (TyG) index and prognosis in critically ill patients with acute coronary syndrome (ACS), exploring potential heterogeneity of the association among patient subgroups with different characteristics. Methods: Records of patients with ACS were extracted from the MIMIC-IV database. The association between TyG index and mortality was analyzed using Cox proportional-hazard regression model, while potential non-linear associations were assessed using restricted cubic spline (RCS) regression. Meanwhile, linear regression model was used to explore the association between TyG index and length of stay in hospital or ICU. Subpopulation Treatment Effect Pattern Plot (STEPP) was utilized to explore the

SUBMITTER: Chen M 

PROVIDER: S-EPMC11905271 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature