Long-latency gamma modulation after median nerve stimulation delineates the central sulcus and contrasts the states of consciousness.

ABSTRACT:

Objective

To evaluate the functional use of sub-band modulations in somatosensory evoked potentials (SSEPs) to discriminate between the primary somatosensory (S1) and motor (M1) areas and contrast the states of consciousness.

Methods

During routine intraoperative cortical mapping, SSEPs were recorded with electrocorticography (ECoG) grids from the sensorimotor cortex of eight patients in the anesthetized and awake states. We conducted a time-frequency analysis on the SSEP trace to extract the spectral modulations in each state and visualize their spatial topography.

Results

We observed late gamma modulation (60-250 Hz) in all subjects approximately 50 ms after stimulation onset, extending up to 250 ms in each state. The late gamma activity enhancement was predominant

SUBMITTER: Asman P 

PROVIDER: S-EPMC11905291 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature