Integrated analysis of differential expression profile of miRNA in the uterus of seasonal estrus sheep.

ABSTRACT:

Background

Photoperiod is one of the important factors affecting seasonal estrus of sheep. The importance of the uterus to reproduction is self-evident. However, the uterine molecular mechanisms involved in photoperiodic regulation of seasonal estrus events in sheep remain poorly understood. In recent years, the role of uterine microRNA (miRNA) in mammalian reproduction has been continuously revealed, and it is necessary to analyze and discuss their participation in the seasonal estrus of sheep.

Results

We compared the miRNA expression profile in uterine tissues of Sunit sheep at 3 different photoperiods, short photoperiod (SP), short transfer to long photoperiod (SLP), and long photoperiod (LP). The results showed that 31, 29 and 21 differentially expressed miRNA (DEM) were

SUBMITTER: Yang F 

PROVIDER: S-EPMC11905465 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature