Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study.

ABSTRACT:

Background

Bronchodilator responsiveness testing is mainly used for diagnosing asthma. We aimed to investigate whether it is associated with progression to chronic airflow obstruction over time.

Methods

The multinational Burden of Obstructive Lung Disease cohort study surveyed adults, aged 40 years and above, at baseline and followed them up after a mean of 9.1 years. Recruitment took place between January 2, 2003 and December 26, 2016. Follow-up measurements were collected between January 29, 2019 and October 24, 2021. On both occasions, study participants provided information on respiratory symptoms, health status and several environmental and lifestyle exposures. They also underwent pre- and post-bronchodilator spirometry. We defined bronchodilator responsiveness at basel

SUBMITTER: Knox-Brown B 

PROVIDER: S-EPMC11905823 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature