Propofol-based deep sedation for colonoscopy: does sufentanil, alfentanil or ketamine help? A propensity score weighted retrospective study.

ABSTRACT:

Introduction

Gastrointestinal endoscopy is a frequent procedure for diagnosing and following up on various digestive disorders. It is often conducted under propofol sedation. The aim of this work is, first, to determine whether the addition of sufentanil, alfentanil, or ketamine to propofol has a propofol-sparing effect and, secondarily, how these drugs affect the patients' hemodynamic parameters and oxygenation as well as the duration of the procedure.

Methods

Data from patients who underwent colonoscopy were extracted from the anesthesia records database and divided into four groups. Patients received either propofol or a combination of propofol and sufentanil, alfentanil, or ketamine. After inverse propensity weighting, we determined the average treatment effects for each

SUBMITTER: Fostier M 

PROVIDER: S-EPMC11905911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature