Treatment strategies for non-responders to oral iron and folic acid treatment in anemic children: A systematic review.

ABSTRACT: Background Iron and folic acid (IFA) are essential nutrients, with deficiencies associated not only with anemia but also with other significant health consequences, including impaired cognitive development, increased susceptibility to infections, and adverse pregnancy outcomes. Despite the widespread use of IFA for management, a notable percentage of individuals failed to respond resulting in persistent anemia. This systematic review investigates the management of non-responders to oral iron and folic acid (IFA) treatment, among children under five. Non-responders are anemic individuals who do not recover after the standard IFA treatment. A comprehensive search was conducted across multiple databases including Medline, Cochrane, Embase, and Google Scholar, covering the period from January

SUBMITTER: Manapurath R 

PROVIDER: S-EPMC11906079 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature