Finasteride Use: Evaluation of Depression and Suicide Risk.

ABSTRACT:

Background

Oral finasteride 1 mg/day is indicated for androgenetic alopecia (AGA), while 5 mg/day is for benign prostatic hyperplasia (BPH). Oral finasteride has been linked with depression and suicide; however, a causal association is uncertain. The so-called post-finasteride syndrome (PFS) refers to a "cluster" of side effects experienced by some men (i.e., cis men) after taking oral finasteride.

Aims

The objective of the current study was to evaluate the association of depression and suicide with oral finasteride in males, using data from the United States Food and Drug Administration Adverse Event Reporting System (FAERS). As a secondary objective, we conducted disproportionality analyses of FAERS data to assess whether oral dutasteride use was linked to psychological sy

SUBMITTER: Gupta AK 

PROVIDER: S-EPMC11906302 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature