Association between METS-IR and female infertility: a cross-sectional study of NHANES 2013-2018.

ABSTRACT:

Background

Obesity and metabolic syndrome are significant contributors to infertility in women and are closely associated with insulin resistance (IR). The metabolic score for insulin resistance (METS-IR) is a new, non-insulin-based fasting index used to measure IR. However, the potential of METS-IR as a predictive indicator of female infertility risk has not been established. This study aimed to explore the association between METS-IR and the risk of female infertility.

Methods

This cross-sectional study used data from the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2018. We conducted multivariate logistic regression, restricted cubic spline (RCS), and threshold effect analyses to investigate the relationship between METS-IR and female infertility

SUBMITTER: Li H 

PROVIDER: S-EPMC11906314 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature