Relationship between ghrelin and thyroid disease: a meta-analysis.

ABSTRACT:

Background

Previous studies have identified a close relationship between ghrelin levels and thyroid disease. Ghrelin levels were lower in patients with hyperthyroidism compared with healthy individuals, and increased after treatment. However, other studies have reported inconsistent results. As such, the association between ghrelin and thyroid disease remains controversial.

Methods

A literature search of the Web of Science, Wiley Online Library, Embase, and PubMed databases was performed. The title or abstract search term "thyroid" was used in combination with "ghrelin". Meta-analysis results are reported as standardized mean difference with corresponding 95% confidence interval (CI).

Results

Twenty-three studies were included in this meta-analysis. Ghrelin levels in

SUBMITTER: Xin C 

PROVIDER: S-EPMC11906317 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature