Estimation of Inbreeding Depression From Overdominant Loci Using Molecular Markers.

ABSTRACT: Inbreeding depression is a highly relevant universal phenomenon in population and conservation genetics since it leads to a decline in the fitness of individuals. This phenomenon is due to the homozygous expression of alleles whose effects are hidden in heterozygotes (inbreeding load). The rate of inbreeding depression for quantitative traits can be quantified if the coefficient of inbreeding (F) of individuals is known. This coefficient can be estimated from pedigrees or from the information of molecular markers, such as SNPs, using measures of homozygosity of individual markers or runs of homozygosity (ROH) across the genome. Several studies have investigated the accuracy of different F measures to estimate inbreeding depression, but always assuming that this is only due to

SUBMITTER: Gonzalez-Castellano I 

PROVIDER: S-EPMC11906488 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature