Alterations in nailfold videocapillaroscopy among patients with connective tissue diseases combined with pulmonary arterial hypertension: A cross-sectional study.

ABSTRACT: This study examines the correlation between nailfold videocapillaroscopy (NVC) abnormalities and pulmonary hypertension (PH) in connective tissue disease (CTD) patients, evaluating its diagnostic and predictive value for microcirculation alterations. A cross-sectional study included 351 CTD patients and 30 non-CTD healthy people, with NVC assessments conducted qualitatively, semi-quantitatively, and quantitatively by two independent physicians. Clinical and laboratory data were analyzed, comparing CTD patients with pulmonary arterial hypertension (CTD-PAH) and those without (CTD-non-PAH). Among the patients, 16.5% (n = 58) had pulmonary hypertension. CTD-PAH patients showed higher nailfold videocapillaroscopy scores (5.73 ± 3.54 vs. 4.30 ± 2.98, P = 0.001) and larger capillary diameters (1

SUBMITTER: Tang Z 

PROVIDER: S-EPMC11906740 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature