Contributions of interspecific hybrids to genetic variability in Glycyrrhiza uralensis and G. glabra.

ABSTRACT: Licorice (Glycyrrhiza L.), a medicinally and economically significant genus in the Fabaceae, is known for synthesizing glycyrrhizin. Here, we present a newly assembled genome of Glycyrrhiza uralensis, a key species distributed across Central and East Asia. Using Oxford Nanopore, Hi-C, and Illumina sequencing, we assembled a 415 Mbp genome with an N50 of 47 Mbp. While the genome structure was similar to previously reported assemblies, structural variations were observed across all eight chromosomes. Re-sequencing data from 29 individuals, including G. uralensis, G. glabra, and their hybrids, revealed significant genetic diversity, population structure, and hybridization events. Phylogenomic analyses using nuclear and plastid genomes demonstrated phylogenetic incongruence, supporting hybridi

SUBMITTER: Kim J 

PROVIDER: S-EPMC11906797 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature