Enhanced electrochemical detection of dopamine and uric acid using Au@Ni-MOF and employing 2D structure DFT simulation.

ABSTRACT: The accurate and expeditious detection of minute biomolecules within human body fluids holds paramount significance in the advancement of novel electrode materials. In this research, a novel non-enzyme electrochemical sensor was constructed. It was founded on Au@Ni-MOF (Ni(CH₃CO₂)₂) hybrids, with Ni(II) (nickel acetate) serving as the precursor. Specifically, [Ni₃(BTC)₂]_n (H₃BTC = 1,3,5-trimesic acid) featuring coordinatively unsaturated Ni(II) sites and decorated with gold nanoparticles was synthesized via an in-situ growth methodology. The Au@Ni-MOF hybrids exhibit outstanding electrochemical and electrocatalytic characteristics, attributable to the meticulous assembly of AuNPs and Ni-MOF. The Au@Ni-MOF (Ni(CH

SUBMITTER: Zhou F 

PROVIDER: S-EPMC11906810 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature