Cross-sectional associations between multiple plasma heavy metals and lung function among elderly Chinese.

ABSTRACT: Environmental exposure to heavy metals may adversely affect lung function particularly in the elderly. However, limited data are available directly evaluating the relationship of heavy metal exposures with lung function in Chinese elderly. We aimed to investigate the associations between plasma metals and lung function among Chinese elderly residents. We conducted a cross-sectional study of 308 elderly residents in an industrial area and a non-industrial area in northwest China and estimated the single and combined effects of plasma metals and their interactions with lung functions (forced vital capacity [FVC], forced expiratory volume in 1 s [FEV1], and FEV1/FVC). We analyzed 12 plasma metals and identified 4 metals by lasso regression and BKMR model for further analysis. Bayesian kernel

SUBMITTER: Yu J 

PROVIDER: S-EPMC11906836 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature