Multivitamin supplementation and its impact in metabolic dysfunction-associated steatotic liver disease.

ABSTRACT: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an emerging global health concern with limited therapeutic options. Multivitamins, widely consumed dietary supplements, have been proposed to modulate oxidative stress and inflammation, potentially impacting MASLD progression. However, their efficacy in reducing mortality and other complications in MASLD remains unclear. Using data from the UK Biobank with 7 years of median follow-up period, this study assessed the association between multivitamin use and health outcomes, including all-cause mortality, liver-related mortality, cardio-cerebrovascular disease (CVD), and chronic kidney disease (CKD), in individuals with MASLD and those without steatotic liver disease. Inverse probability of treatment weighting (IPTW) was empl

SUBMITTER: Ryu T 

PROVIDER: S-EPMC11906897 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature