Comparative toxicity and environmental impact assessments of sonochemically-synthesized CuO and Zn-doped CuO nanoparticles using zebrafish and LCA tools.

ABSTRACT: Nanomaterials (NMs), including nanoparticles (NPs), offer promising potential in achieving the European Commission's Green Deal goals of climate-neutral, zero-pollution and circular economy. Metal oxide NPs display antimicrobial properties, with efficacy also towards antimicrobial-resistant bacteria. Nevertheless, the increasing manufacture, use and unintended release of NMs particularly in aquatic compartments, raises concerns about their environmental sustainability and safety towards non-target organisms. Within the Safe and Sustainable by Design framework, this study compares toxicity and environmental impacts of sonochemically synthesized water-based CuO and Zn-doped CuO NPs. Zebrafish embryos were exploited in a high-throughput developmental and behavioral screening to investigate na

SUBMITTER: Negrini B 

PROVIDER: S-EPMC11906939 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature