Synergistic Artemisia monosperma with royal jelly: antibacterial, antioxidant, antibiofilm, and anti-Alzheimer assay.

ABSTRACT: This investigation aimed to examine the synergistic effects of fresh royal jelly and local wild Artemisia monosperma leaf extract as antibacterial, antioxidant, antibiofilm, and anti-Alzheimer activity. Gas chromatography-mass spectrometry (GC-MS) identified 16 compounds in Artemisia monosperma, including tricosadiynoic acid, hexadecenoic acid, octadecenoic acid. In contrast, fresh royal jelly contained 13 compounds, including dodecanoic acid, octadecynoic acid, hexadecenoic acid, heptatriacotanol, and their derivatives. The Artemisia monosperma extract exhibited significant antioxidant activity in the DPPH assay, with IC₅₀ value of 5.48 ± 0.002 µg/mL. Fresh royal jelly exhibited an IC₅₀ value of 14.56 ± 0.004 µg/mL. Both substances exhibited significant antibacterial

SUBMITTER: Elshafey N 

PROVIDER: S-EPMC11906961 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature