Positive association between serum lactate dehydrogenase levels and blood pressure: evidence from NHANES 2015-2016.

ABSTRACT:

Background

Serum lactate dehydrogenase (sLDH) is an enzyme implicated in tissue injury and inflammatory responses. Despite its established role in these pathophysiological processes, the association between sLDH and blood pressure remains underexplored. The present findings suggest that sLDH could emerge as a valuable biomarker for blood pressure regulation and may hold significant promise in the management of hypertension.

Methods

Our investigation utilized data from the National Health and Nutrition Examination Survey (NHANES) 2015-2016, comprising 3,469 participants after excluding those under the age of 20, individuals on antihypertensive therapies, and cases with incomplete data. sLDH levels were categorized into tertiles, while blood pressure measurements were conducte

SUBMITTER: Hu T 

PROVIDER: S-EPMC11906999 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature