Cost-effectiveness analysis comparing QuantiFERON test and tuberculin skin test for the diagnosis of latent tuberculosis infection in immunocompetent children under 15 years of age in Colombia.

ABSTRACT:

Objective

To determine the cost-effectiveness of the QuantiFERON (QFT) test versus the tuberculin skin test (TST) in diagnosing latent tuberculosis infection (LTBI) in immunocompetent children under 15 years of age who are in contact with active tuberculosis (TB) patients in the context of the Colombian healthcare system.

Design

Health economic evaluation. Decision tree over a horizon of <1 year.

Setting

From the perspective of the Colombian healthcare system, the direct healthcare costs related to tests were considered, and diagnostic performance was used as a measure of effectiveness. The currency was the US dollar (US$) for the year 2022, with a cost-effectiveness threshold of US$6666.

Participants

A simulated hypothetical cohort of 2000 immunocompetent chil

SUBMITTER: Navarro CE 

PROVIDER: S-EPMC11907012 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature