A Comprehensive Skin Gas Analysis of Substances Related to Uraemia in Patients With End-Stage Kidney Disease: A Pilot Study.

ABSTRACT: Recent progress in gas-sensing technology has enabled the rapid collection and highly sensitive analysis of skin gases associated with body odour. Skin gases can be collected less invasively, more continuously, and less consciously than blood or urine. Patients with end-stage kidney disease (ESKD) have a characteristic uremic odour that fades after initiating kidney replacement therapy. We investigated the potential for objectively and quantitatively evaluating the factors underlying uraemia. Skin gases were collected using a passive flux sampler placed on the forearm, with peak intensities measured using gas chromatography-mass spectrometry (GC/MS). We investigated the changes in skin gases obtained from the haemodialysis (HD) group before and after the first HD session of patients underg

SUBMITTER: Hashiba T 

PROVIDER: S-EPMC11907091 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature