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Narrative review on ethical and psychological issues raised by genetic and genomic testing in pediatric oncology care.


ABSTRACT: In pediatric oncology, genetic and genomic tests are proposed throughout the care pathway for many reasons (e.g., cancer characterization, identification of the most appropriate treatment, patient selection for clinical trials, identification of tissue/organ donors, or risk of relapse prediction). Despite the many different approaches (somatic or germline testing, targeted gene or genome sequencing), the implicated individuals are confronted with situations that may intersect and that are interesting to compare. No study has identified and analyzed the available works on these new practices in pediatric oncology. The aim of this narrative literature review was to describe the ethical and psychological perspectives of children with cancer, parents, and healthcare professionals when genetic

SUBMITTER: Droin-Mollard M 

PROVIDER: S-EPMC11907175 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature