GLP-1RA Use and Thyroid Cancer Risk.

ABSTRACT:

Importance

The increasing use of glucagon-like peptide-1 receptor agonists (GLP-1RA) demands a better understanding of their association with thyroid cancer.

Objective

To estimate the risk of incident thyroid cancer among adults with type 2 diabetes being treated with GLP-1RA vs other common glucose-lowering medications.

Design, setting, and participants

This was a prespecified secondary analysis of a target trial emulation of a comparative effectiveness study using claims data for enrollees in commercial, Medicare Advantage, and Medicare fee-for-service plans across the US. Eligible participants were adults with type 2 diabetes at moderate risk for cardiovascular disease and without history of thyroid cancer who had newly filled prescriptions for GLP-1RA, sodium-gluc

SUBMITTER: Brito JP 

PROVIDER: S-EPMC11907303 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature