Analysis of central corneal thickness in systemic lupus erythematosus.

ABSTRACT:

Introduction

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with ocular involvement in up to 30% of cases. Due to its type I collagen composition, the cornea is particularly susceptible to thinning due to immune-complex deposition. A reduced central corneal thickness (CCT) is clinically relevant in glaucoma, where a thinner CCT increases glaucoma risk and in refractive surgery planning. Previous studies on CCT in SLE are limited due to methodological heterogeneity, technology use, inclusion criteria, and sample size, resulting in conflicting findings. This study aims to evaluate and compare the mean CCT values between patients with SLE and healthy controls.

Materials and methods

This cross-sectional study assessed mean CCT in 71 participants, 36 patients

SUBMITTER: Saldana-Garrido JD 

PROVIDER: S-EPMC11907372 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature