Prognostic value of HER2 expression in cervical adenocarcinoma:  A retrospective cohort study.

ABSTRACT: Human epidermal growth factor receptor 2 (HER2) is an important therapeutic target in various types of cancer, although the prognostic value and therapeutic potential of HER2 in cervical adenocarcinoma are still underexplored. The present study aimed to examine the association between HER2 expression levels and prognosis in cervical adenocarcinoma, offering new insights into targeted therapies for HER2-expressing cervical adenocarcinoma. A total of 179 patients with cervical cancer who received surgery were included, and HER2 status in surgical specimens of the included patients were assessed using two classification methods: Immunohistochemistry (IHC) alone and traditional combined IHC/fluorescence in situ hybridization (FISH). IHC alone was used to categorize patients into the HER

SUBMITTER: Xu Q 

PROVIDER: S-EPMC11907399 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature