Associations between multimorbidity and kidney function decline in old age: A population-based cohort study.

ABSTRACT:

Background

Individual chronic conditions have been linked to kidney function decline; however, the role of multimorbidity (the presence of ≥2 conditions) and multimorbidity patterns remains unclear.

Methods

A total of 3094 individuals from the Swedish National study on Aging and Care in Kungsholmen (SNAC-K) were followed for 15 years. Multimorbidity was operationalized as the number of chronic conditions and multimorbidity patterns identified using latent class analysis (LCA). Joint models and Cox regression models were used to explore the associations between multimorbidity, and subsequent absolute and relative (≥25% decline from baseline) changes, respectively, in the estimated glomerular filtration rate (eGFR) calculated using the creatinine-based Berlin Initiative Study

SUBMITTER: Beridze G 

PROVIDER: S-EPMC11907758 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature