Indications for extracorporeal membrane oxygenation in older adult patients with accidental hypothermia and hemodynamic instability.

ABSTRACT:

Background

Extracorporeal membrane oxygenation (ECMO) indications in patients with accidental hypothermia (AH) and hemodynamic instability before cardiac arrest (CA) are unclear. We aimed to identify a subgroup of these patients who would benefit from ECMO rewarming.

Methods

This study was a post-hoc analysis of the ICE-CRASH study (2019-2022), a prospective, multicenter, observational study throughout Japan. Among the 499 patients (core temperature < 32 °C, age > 18 years), 175 with AH and hemodynamic instability were selected. The primary outcome was 28-day mortality. We examined the effect of ECMO on 28-day mortality after risk stratification based on age, activities of daily living (ADLs), core temperature, Glasgow coma scale (GCS) score, systolic blood pressure (SBP), a

SUBMITTER: Takauji S 

PROVIDER: S-EPMC11907841 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature