Impact of comorbidities on management and outcomes of patients weaning from invasive mechanical ventilation: insights from the WEAN SAFE study.

ABSTRACT:

Background

The impact of comorbidities on patients weaning from invasive ventilation is incompletely understood. We wished to understand the impact of the number and type of comorbidities on patients' weaning from invasive mechanical ventilation enrolled in the 'WorldwidE AssessmeNt of Separation of pAtients From ventilatory assistancE (WEAN SAFE) study.

Methods

The study population consisted of patients enrolled in the WEAN SAFE study that commenced the weaning process. We categorized patients by the number of comorbidities (none, 1, 2, or 3 plus), and by specific comorbidity type. The primary outcome was the impact of comorbidities on delayed weaning and failed weaning from invasive MV. Secondary outcomes included the impact of comorbidities on ICU and hospital survival, a

SUBMITTER: Khazaei O 

PROVIDER: S-EPMC11907859 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature