Impacts of zinc caproate supplementation on growth performance, intestinal health, anti-inflammatory activity, and Zn homeostasis in weaned piglets challenged with Escherichia coli K88.

ABSTRACT:

Background

Enterotoxigenic Escherichia coli (ETEC) is one of the primary causes of diarrhea in piglets, creating substantial economic losses in the swine farming industry worldwide. This study aimed to investigate the impacts of zinc caproate (ZnCA, C₁₂H₂₂O₄Zn) on the intestinal health, growth performance, inflammatory status, and Zn homeostasis of weaned piglets challenged with ETEC K88. In total, 48 weaned piglets (Duroc × Landrace × Yorkshire, 7.78 ± 0.19 kg, 28 d) were selected for a 21-d experiment. Each experimental treatment consisted of 6 replicate pens with 2 piglets each. The treatment conditions were as follows: i) a basal diet (CON), ii) a basal diet + ETEC K88 (NC), iii) a basal diet + 2,500 mg/kg of Zn (provided as zinc oxide, ZnO) + E

SUBMITTER: Xu J 

PROVIDER: S-EPMC11908000 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature