Terminologies and definitions used to classify patients with osteoarthritis: a scoping review.

ABSTRACT:

Objectives

Osteoarthritis (OA), a prevalent and disabling condition, significantly burdens individuals and healthcare systems worldwide. It is characterized by joint pain, stiffness, and structural changes in cartilage, bone, and synovium. The clinical manifestations of OA vary widely, reflecting complex interactions among genetic, metabolic, biomechanical, and environmental factors. Despite progress in identifying OA clinical phenotypes, inconsistent terminology, including "phenotypes," "subtypes," and "subgroups," hinders effective communication and research translation. This review aims to synthesize existing literature on clinical OA phenotypes, terminology, and definitions and propose a research agenda.

Method

This scoping review followed PRISMA-ScR guidelines, focusing

SUBMITTER: Gijon-Nogueron G 

PROVIDER: S-EPMC11908012 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature