One in three adenomas could be missed by white-light colonoscopy - findings from a systematic review and meta-analysis.

ABSTRACT:

Background

White light (conventional) colonoscopy (WLC) is widely used for colorectal cancer screening, diagnosis and surveillance but endoscopists may fail to detect adenomas. Our goal was to assess and synthesize overall and subgroup-specific adenoma miss rates (AMR) of WLC in daily practice.

Methods

We conducted a systematic review in MEDLINE, EMBASE, Cochrane Library, and grey literature on studies evaluating diagnostic WLC accuracy in tandem studies with novel-colonoscopic technologies (NCT) in subjects undergoing screening, diagnostic or surveillance colonoscopy. Information on study design, AMR overall and specific for adenoma size, histology, location, morphology and further outcomes were extracted and reported in standardized evidence tables. Study quality was asses

SUBMITTER: Jahn B 

PROVIDER: S-EPMC11908064 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature