Node-reconfiguring multilayer networks of human brain function.

ABSTRACT: Functional brain network properties are heavily influenced by how the the network nodes are defined. A common approach uses Regions of Interest (ROIs), i.e., predetermined collections of functional magnetic resonance imaging (fMRI) measurement voxels, as nodes. Their definition is always a compromise, as static ROIs cannot capture the dynamics and temporal reconfigurations of the brain areas. Consequently, the ROIs do not align with the functionally homogeneous regions, which can explain the low functional homogeneity values observed for the ROIs. This is in violation of the underlying homogeneity assumption in functional brain network analysis pipelines, which can cause serious problems such as spurious network structure. We introduce the node-reconfiguring multilayer network model, where

SUBMITTER: Nurmi T 

PROVIDER: S-EPMC11908370 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature