The global, regional and national burden of peptic ulcer disease attributable to smoking from 1990 to 2021: A population-based study.

ABSTRACT:

Background

Peptic ulcer disease (PUD) remains a significant global health challenge, with its prevalence generally declining due to advances in healthcare and reduction in key risk factors. However, smoking continues to be a major contributor to the burden of PUD. This study analyzes the temporal and spatial patterns of PUD burden attributable to smoking globally from 1990 to 2021, providing insights for public health interventions.

Methods

Utilizing data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 database, we assessed deaths, disability-adjusted life years (DALYs), age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR). Trends from 1990 to 2021 were evaluated using average annual percentage change (AAPC), and predi

SUBMITTER: Wang S 

PROVIDER: S-EPMC11908546 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature