Randomized trial of ultraviolet irradiation units installed in homes of children and adolescents with asthma.

ABSTRACT:

Background

Asthma management involves medications with environmental control, but patient adherence to the latter is poor. A previous pilot study found an ultraviolet indoor air-irradiation system (CREON2000A) was effective in reducing asthma severity in children with mild to moderate asthma.

Objective

This trial's purpose was to confirm these results in a larger population over a longer time duration.

Methods

A 12-month randomized, sham device-controlled multicenter study enrolled 79 children with mild to moderate persistent asthma aged 6 to <18 years. Participants were randomized to have a CREON2000A ultraviolet air irradiation device or a sham device installed in their home's ventilation system. Enrolled children were assessed with the Composite Asthma Severity Ind

SUBMITTER: Bernstein JA 

PROVIDER: S-EPMC11908574 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature