Cortical hemodynamics of electrographic status epilepticus in the critically ill.

ABSTRACT:

Objectives

The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near-infrared spectroscopy (fNIRS) combined with video-electroencephalography (vEEG) to monitor brain hemodynamics continuously and non-invasively in critically ill adult patients experiencing electrographic SE. Our primary focus is to investigate neurovascular coupling and cerebrovascular changes associated with seizures, particularly during recurring and/or prolonged episodes.

Methods

Eleven critically ill adult patients underwent simultaneous vEEG-fNIRS with large cortical coverage. Data from seven patients with identified electrographic SE were analyzed. The timing of recorded seizures was marked using stan

SUBMITTER: Kassab A 

PROVIDER: S-EPMC11908672 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature