Cerebral artery and brain pathology correlates of antemortem cerebral artery 4D flow MRI.

ABSTRACT: Large-scale clinical research studies often incorporate neuroimaging biomarkers to understand underlying pathologic changes that occur in aging and neurodegenerative disease and are associated with cognitive decline and clinical impairment. Of particular interest are neuroimaging methods designed to understand various aspects of cerebrovascular disease that can lead to dementia and also co-occur with neurodegenerative diseases such as Alzheimer's disease. Neurovascular 4D flow magnetic resonance imaging is one such method that measures hemodynamic characteristics of medium-large cerebral vessels, but it remains unclear how measures derived from 4D flow imaging including pulsatility index, cerebral blood flow, and cross-sectional area relate to underlying pathologic changes in cerebral arte

SUBMITTER: Schroeder BE 

PROVIDER: S-EPMC11908694 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature