Brain Volume Metric Analysis Is Correlated with Aging Changes and Sex Differences in Thai Older Adults.

ABSTRACT:

Introduction

Normative data on structural brain volume changes with age and sex differences are required as a reference standard for future research and clinical use.

Methods

We studied a two-center, metropolitan-based, prospective cohort of adults aged 55 years and older who were recruited from community-dwelling settings and outpatient clinics without cognitive impairment at baseline and who were followed up for 2 years. The clinical data, neuropsychological tests, and brain MRI obtained with FreeSurfer software were utilized for quantitative volumetric measurements.

Results

A total of 296 participants were recruited at the beginning, with 17 participants (5.8%, excluding 2 subjects with claustrophobia) excluded due to abnormal MRI findings and 27 participants (9.1%

SUBMITTER: Muangpaisan W 

PROVIDER: S-EPMC11908812 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature