Imaging Biomarker Studies of Antipsychotic-Naive First-Episode Schizophrenia in China: Progress and Future Directions.

ABSTRACT:

Background and hypothesis

Identifying biomarkers at onset and specifying the progression over the early course of schizophrenia is critical for better understanding of illness pathophysiology and providing novel information relevant to illness prognosis and treatment selection. Studies of antipsychotic-naïve first-episode schizophrenia in China are making contributions to this goal.

Study design

A review was conducted for how antipsychotic-naïve first-episode patients were identified and studied, the investigated biological measures, with a focus on neuroimaging, and how they extend the understanding of schizophrenia regarding the illness-related brain abnormality, treatment effect characterization and outcome prediction, and subtype discovery and patient stratification, in

SUBMITTER: Zhang W 

PROVIDER: S-EPMC11908865 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature