A Developmental Perspective on Early and Current Motor Abnormalities and Psychotic-Like Symptoms.

ABSTRACT:

Background and hypothesis

Psychotic-like experiences (PLEs) are prevalent in the general population and, because they represent a lower end of the psychosis vulnerability spectrum, may be useful in informing mechanistic understanding. Although it is well-understood that motor signs characterize formal psychotic disorders, the developmental trajectory of these features and their relationships with PLEs are less well-understood.

Study design

Data from 7559 adolescents and young adults (age 11-21) in the Philadelphia Neurodevelopmental Cohort were used to investigate whether early-life milestone-attainment delays relate to current adolescent sensorimotor functioning and positive and negative PLEs. Current sensorimotor functioning was assessed using the Computerized Finger Tappi

SUBMITTER: Fattal J 

PROVIDER: S-EPMC11908870 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature