The association between initial defibrillation dose and outcomes following adult out-of-hospital cardiac arrest resuscitation: A retrospective, multi-agency study.

ABSTRACT:

Introduction

Effective defibrillation is essential to out-of-hospital cardiac arrest (OHCA) survival. International guidelines recommend initial defibrillation energies between 120 and 360 Joules, which has led to widespread practice variation. Leveraging this natural experiment, we aimed to explore the association between initial defibrillation dose and outcome following OHCA.

Methods

The ESO Data Collaborative (2018-2022) was used for this nationwide, retrospective study of adult (18-80 years of age) non-traumatic OHCA patients who presented with an initially shockable ECG rhythm. We excluded patients if they had ROSC prior to initial defibrillation, a resuscitation-limiting advanced directive, or were residents in a healthcare institution. The primary exposure was initial

SUBMITTER: Smida T 

PROVIDER: S-EPMC11908921 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature