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Exploring the relationship between frailty and nonunion fractures in upper extremity injuries: insights from the national inpatient sample.


ABSTRACT:

Introduction

Frailty, a physiological decline in functional capacity, may influence nonunion risk. This study aimed to investigate the association between frailty, as measured by the modified Frailty Index-5 (mFI-5), and the likelihood of nonunion fractures of the upper extremity.

Methods

This retrospective cohort study utilized the national inpatient sample (NIS) from 2015 to 2019. Patients aged 18 and older with upper extremity fractures, identified by ICD-10-CM codes, were included. Patients were categorized into routine healing and nonunion groups. Frailty was assessed using the mFI-5, classifying patients as robust, prefrail, frail, or severely frail. Multivariate logistic regression, controlling for age, sex, and Injury Severity Score (ISS), was performed to determine

SUBMITTER: Luczkow C 

PROVIDER: S-EPMC11909083 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature