Visceral adipose tissue is related to interleukin 6 and resistin in juvenile idiopathic arthritis - a case-control study.

ABSTRACT: To compare visceral adipose tissue (VAT) mass, lipid profile, and selected adipokines/cytokines in patients with juvenile idiopathic arthritis (JIA) with controls, and to explore associations between these markers and VAT. We included 60 JIA patients (30 oligoarticular,30 polyarticular), aged 10-16 years, and 60 age-and sex-matched controls. VAT (g) was estimated by dual-energy x-ray absorptiometry. Lipid profile and selected adipokines/cytokines were analyzed by standard methods and ELISA, respectively. VAT (g) was comparable between patients and controls [median (25th-75th percentile): 64 (23-149) g vs. 66 (30-99) g, p = 0.98] and between oligoarticular and polyarticular disease courses [46 (22-123) g vs. 80 (23-167) g, p = 0.32]. Patients had lower serum levels of apolipoprotein A1 (APO

SUBMITTER: Risum K 

PROVIDER: S-EPMC11909091 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature