Preoperative brain volume loss is associated with postoperative delirium in advanced heart failure patients supported by left ventricular assist device.

ABSTRACT: Delirium is a common neurological complication in patients with advanced heart failure (ADHF) following left ventricular assist device (LVAD) implantation, significantly impacting recovery. This study aimed to analyze non-contrast computed tomography (CT) scans of the brain in ADHF patients undergoing LVAD implantation to determine the association between pre-existing brain atrophy and postoperative delirium. A study involving 166 ADHF patients was conducted from March 2020 to July 2023. Non-contrast CT scans were analyzed using advanced quantitative neuroimaging techniques before implantation. The primary marker assessed was the lateral ventricle fraction (LVF), with secondary markers including cortical gray matter fraction (cGMF), white matter fraction (WMF), basal ganglia fraction (BGF)

SUBMITTER: Murrieta-Alvarez I 

PROVIDER: S-EPMC11909272 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature