Efficacy and safety of idiopathic normal pressure hydrocephalus shunting: a systematic review and meta-analysis.

ABSTRACT:

Objective

Shunting is commonly used in patients with idiopathic normal pressure hydrocephalus (iNPH). However, evidence comparing the relative effectiveness and safety of different iNPH shunting methods is lacking. Therefore, this systematic review investigated the efficacy and safety of different iNPH shunts.

Methods

The PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science databases were systematically searched for articles comparing iNPH shunting from inception to July 29th, 2023 to identify randomized controlled trails or cohort studies comparing iNPH shunting with placebo or other treatment. Evidence was summarized using fixed and randomized effects frequentist meta-analysis when the I² was <50% and >50%, respectively. S

SUBMITTER: Liu X 

PROVIDER: S-EPMC11909566 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature