Temporal trends, clinical characteristics and prognostic factors analysis of infective endocarditis: a multicenter ambispective cohort study in China.

ABSTRACT:

Background

The epidemiological and clinical characteristics of infective endocarditis (IE) in mainland China, particularly following the COVID-19 pandemic, remain insufficiently understood. This study aims to examine temporal trends, clinical features, and factors influencing in-hospital mortality of IE in northern China from 2019 to 2023.

Methods

This multicenter, retrospective study included 961 patients diagnosed with IE between 2019 and 2023 across hospitals in Henan, Shandong, and Tianjin. Data were collected on demographics, comorbidities, COVID-19 status, and treatment modalities. Risk factors for in-hospital mortality were identified using logistic regression and Cox proportional hazards models. The effect of surgical intervention was assessed through propensity scor

SUBMITTER: Liu J 

PROVIDER: S-EPMC11909911 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature