Caregiver burden and familial impact in Down Syndrome Regression Disorder.

ABSTRACT:

Background

Down Syndrome Regression Disorder (DSRD) is an acute or subacute neurocognitive regression in individuals with Down syndrome (DS), characterized by a loss of previously acquired cognitive, adaptive, and social skills. DSRD profoundly affects individuals' ability to engage in activities of daily living, making them highly dependent on their caregivers who must provide significantly more support than before the DSRD diagnosis. This study aimed to examine caregiver burden, quality of life, and depression among caregivers of individuals with DSRD versus caregivers of those with DS and other neurological disorders (DSN).

Design/methods

In this cross-sectional study, caregivers of individuals with DSRD (n = 228) and DSN (n = 137) were recruited through Children's Hospit

SUBMITTER: Chow K 

PROVIDER: S-EPMC11909950 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature