A brief strategy for the preparation of silk fibroin-copper sulfide-based electrospun nanofibrous membranes with photothermal antimicrobial properties to accelerate the infected wound healing.

ABSTRACT: Bacterial infections often hinder the wound-healing process. Antibiotics are commonly used to eradicate bacteria, but long-term use can lead to the development of drug-resistant bacteria. Photothermal therapy (PTT) is a promising technology that utilizes a photothermal agent (PTA) to convert near-infrared radiation into heat, which can eliminate bacteria and has the advantages of being highly effective, controllable, and low drug resistance. In this study, we obtained silk fibroin-copper sulfide nanoparticles(SF/CuS NPs)in situ with excellent photothermal responsive properties by a green synthesis strategy using silk fibroin proteins as biological templates. Then, the SF/CuS NPs were mixed with PVA solution, and the photothermal nanofiber membrane (PVA-SF/CuS) was prepared using the

SUBMITTER: Cai R 

PROVIDER: S-EPMC11910131 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature